| Rage syndrome | |
|---|---|
| Other names | A22, episodic dyscontrol, stimulus-responsive psychomotor epilepsy, Mental lapse aggression syndrome |
 | |
| The Malinois was the first breed to have a specific genetic polymorphism linked to rage syndrome. | |
| Specialty | Neurology |
| Symptoms | |
| Complications | Behavioral euthanasia |
| Usual onset | 1–3 years old |
| Duration | Lifelong |
| Causes | Unknown |
| Risk factors | PolyA(22) (in Malinois), DAT-VNTR (in Malinois), likely other genetic factors, breed, other seizures |
| Diagnostic method | EEG, with complete exclusion of other medical conditions via thorough medical testing |
| Differential diagnosis | Any untreated illness (Pathophysiological aggression) or behavioral condition |
| Prevention | Selective breeding, Health testing (PolyA(22) test, in Malinois) |
| Management | Anticonvulsants, muzzling, barrier use, lifestyle changes |
| Medication | Antiepileptic drugs (Phenobarbital) |
| Prognosis | Generally poor |
Rage syndrome is a rare seizure disorder in dogs, characterized by explosive aggression.[1][2][3]
It is frequently confused with idiopathic aggression, a term for aggression with no identifiable cause. Rage syndrome is most often a misdiagnosis of dogs with an unrelated, but more common, form of aggression. Although the scientific evidence is limited, it is thought to be genetic in origin, and is heritable.[4] It is treated with antiepileptics.[5]
- ^ Cite error: The named reference
Beaver 1980was invoked but never defined (see the help page). - ^ Cite error: The named reference
Reisner 2005was invoked but never defined (see the help page). - ^ Cite error: The named reference
Amat 2009was invoked but never defined (see the help page). - ^ Cite error: The named reference
Dodman 1992was invoked but never defined (see the help page). - ^ Cite error: The named reference
Bowen 2005was invoked but never defined (see the help page).