American geneticist (born 1928–2008)
Ray Jui Wu
Born Jui Wu
(1928-08-14 ) August 14, 1928Died February 10, 2008(2008-02-10) (aged 79) Nationality American Other names Wu Rui, Wu Jui Alma mater University of Pennsylvania Scientific career Thesis Studies on the Mechanisms of Pyrimidine Biosynthesis (1955) Doctoral advisor D. Wright Wilson Doctoral students Jack W. Szostak
Ray Jui Wu (Chinese : 吴瑞 ; pinyin : Wú Ruì ; Wade–Giles : Wu Jui , 14 August 1928 – 10 February 2008) was a Chinese-born American geneticist and served as Liberty Hyde Bailey Professor of Molecular Genetics and Biology at Cornell University .[ 1]
In 1970, Wu created the first approach for DNA sequencing,[ 2] earlier than the Frederick Sanger's method in 1975 [ 3] and Walter Gilbert 's chemical procedure in 1977.[ 4] Wu's contributions on DNA sequencing are fundamental to the general sequencing methods today.[ 5] [ 6] [ 7]
^ "Ray Wu, Cornell's acclaimed pioneer of genetic engineering and developer of widely grown, hardy rice, dies at 79" . Cornell Chronicle . Retrieved March 27, 2023 .
^ Wu, Ray (August 14, 1970). "Nucleotide sequence analysis of DNA: I. Partial sequence of the cohesive ends of bacteriophage λ and 186 DNA" . Journal of Molecular Biology . 51 (3): 501–521. doi :10.1016/0022-2836(70)90004-5 . ISSN 0022-2836 . PMID 4321727 .
^ Sanger, F.; Coulson, A. R. (May 25, 1975). "A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase" . Journal of Molecular Biology . 94 (3): 441–448. doi :10.1016/0022-2836(75)90213-2 . ISSN 0022-2836 . PMID 1100841 .
^ Maxam, A M; Gilbert, W (February 1977). "A new method for sequencing DNA" . Proceedings of the National Academy of Sciences . 74 (2): 560–564. Bibcode :1977PNAS...74..560M . doi :10.1073/pnas.74.2.560 . ISSN 0027-8424 . PMC 392330 . PMID 265521 .
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^ "Geneticist Ray Wu dies" . The Scientist Magazine® . Retrieved January 12, 2023 .