Ray Wu

Ray Jui Wu
吴瑞
Born
Jui Wu

(1928-08-14)August 14, 1928
Beijing, Republic of China
DiedFebruary 10, 2008(2008-02-10) (aged 79)
NationalityAmerican
Other namesWu Rui, Wu Jui
Alma materUniversity of Pennsylvania
Scientific career
Thesis Studies on the Mechanisms of Pyrimidine Biosynthesis  (1955)
Doctoral advisorD. Wright Wilson
Doctoral studentsJack W. Szostak

Ray Jui Wu (Chinese: 吴瑞; pinyin: Wú Ruì; Wade–Giles: Wu Jui, 14 August 1928 – 10 February 2008) was a Chinese-born American geneticist and served as Liberty Hyde Bailey Professor of Molecular Genetics and Biology at Cornell University.[1]

In 1970, Wu created the first approach for DNA sequencing,[2] earlier than the Frederick Sanger's method in 1975 [3] and Walter Gilbert's chemical procedure in 1977.[4] Wu's contributions on DNA sequencing are fundamental to the general sequencing methods today.[5][6][7]

  1. ^ "Ray Wu, Cornell's acclaimed pioneer of genetic engineering and developer of widely grown, hardy rice, dies at 79". Cornell Chronicle. Retrieved March 27, 2023.
  2. ^ Wu, Ray (August 14, 1970). "Nucleotide sequence analysis of DNA: I. Partial sequence of the cohesive ends of bacteriophage λ and 186 DNA". Journal of Molecular Biology. 51 (3): 501–521. doi:10.1016/0022-2836(70)90004-5. ISSN 0022-2836. PMID 4321727.
  3. ^ Sanger, F.; Coulson, A. R. (May 25, 1975). "A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase". Journal of Molecular Biology. 94 (3): 441–448. doi:10.1016/0022-2836(75)90213-2. ISSN 0022-2836. PMID 1100841.
  4. ^ Maxam, A M; Gilbert, W (February 1977). "A new method for sequencing DNA". Proceedings of the National Academy of Sciences. 74 (2): 560–564. Bibcode:1977PNAS...74..560M. doi:10.1073/pnas.74.2.560. ISSN 0027-8424. PMC 392330. PMID 265521.
  5. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference :1 was invoked but never defined (see the help page).
  7. ^ "Geneticist Ray Wu dies". The Scientist Magazine®. Retrieved January 12, 2023.