Relaxin/insulin-like family peptide receptor 3

RXFP3
Identifiers
Aliases	RXFP3, GPCR135, RLN3R1, RXFPR3, SALPR, Relaxin/insulin-like family peptide receptor 3, relaxin/insulin like family peptide receptor 3, relaxin family peptide receptor 3
External IDs	OMIM: 609445; MGI: 2441827; HomoloGene: 9568; GeneCards: RXFP3; OMA:RXFP3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	33,938,918 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	11,038,077 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; right adrenal cortex; ; left adrenal cortex; ; prefrontal cortex; ; superior frontal gyrus; ; anterior pituitary; ; hypothalamus; ; caudate nucleus; ; substantia nigra; ; head;
	Top expressed in
	embryo; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; hippocampus proper; ; hypothalamus; ; visual cortex; ; neural tube; ; mesencephalon; ; neural layer of retina; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; galanin receptor activity; G protein-coupled peptide receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	positive regulation of cytokinesis; G protein-coupled receptor signaling pathway; phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; neuropeptide signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	51289
	239336
	ENSG00000182631; ENSG00000277069
	ENSMUSG00000060735
	Q9NSD7
	Q8BGE9
	NM_016568
	NM_178717
	NP_057652
	NP_848832
	Wikidata
View/Edit Human	View/Edit Mouse

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.^[5]

^ ^a ^b ^c ENSG00000277069 GRCh38: Ensembl release 89: ENSG00000182631, ENSG00000277069 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060735 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".

[refGRCh38Ensembl-1] ENSG00000277069 GRCh38: Ensembl release 89: ENSG00000182631, ENSG00000277069 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060735 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".

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