Renalase

RNLS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3QJ4
Identifiers
Aliases	RNLS, C10orf59, RENALASE, renalase, FAD-dependent amine oxidase, renalase, FAD dependent amine oxidase
External IDs	OMIM: 609360; MGI: 1915045; HomoloGene: 41254; GeneCards: RNLS; OMA:RNLS - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	88,584,530 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	33,369,695 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; right adrenal gland; ; left adrenal gland; ; right adrenal cortex; ; left adrenal cortex; ; gonad; ; stromal cell of endometrium; ; parotid gland; ; muscle of thigh; ; gastrocnemius muscle;
	Top expressed in
	spermatocyte; ; seminiferous tubule; ; spermatid; ; muscle of thigh; ; soleus muscle; ; right kidney; ; sternocleidomastoid muscle; ; secondary oocyte; ; atrioventricular valve; ; tibialis anterior muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; oxidoreductase activity, acting on NAD(P)H; epinephrine binding; NADH binding; monoamine oxidase activity;
Cellular component	extracellular space; extracellular region;
Biological process	response to ischemia; response to epinephrine; response to salt; response to catecholamine; NAD biosynthesis via nicotinamide riboside salvage pathway; negative regulation of heart rate; negative regulation of blood pressure;
	Sources:Amigo / QuickGO
Orthologs
	55328
	67795
	ENSG00000184719
	ENSMUSG00000071573
	Q5VYX0
	A7RDN6
	NM_001031709; NM_018363
	NM_001146342; NM_001368833; NM_181587
	NP_001026879; NP_060833
	NP_001355762
	Wikidata
View/Edit Human	View/Edit Mouse

Renalase, FAD-dependent amine oxidase is an enzyme that in humans is encoded by the RNLS gene. Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000184719 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000071573 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Renalase, FAD-dependent amine oxidase".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000184719 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000071573 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Renalase, FAD-dependent amine oxidase".

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