Retinoblastoma-like protein 1

RBL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1H28, 4YOO, 4YOS, 4YOZ
Identifiers
Aliases	RBL1, CP107, PRB1, p107, retinoblastoma-like 1, RB transcriptional corepressor like 1
External IDs	OMIM: 116957; MGI: 103300; HomoloGene: 2172; GeneCards: RBL1; OMA:RBL1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	37,095,997 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	157,046,454 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; Achilles tendon; ; ventricular zone; ; testicle; ; ganglionic eminence; ; Skeletal muscle tissue of rectus abdominis; ; bone marrow cells; ; gonad; ; muscle of thigh; ; epithelium of nasopharynx;
	Top expressed in
	Paneth cell; ; hair follicle; ; medial ganglionic eminence; ; dermis; ; spermatocyte; ; vas deferens; ; precursor cell; ; migratory enteric neural crest cell; ; fetal liver hematopoietic progenitor cell; ; renal corpuscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription factor binding; protein binding; promoter-specific chromatin binding; DNA-binding transcription repressor activity, RNA polymerase II-specific;
Cellular component	nucleus; transcription regulator complex; nucleoplasm; chromatin;
Biological process	regulation of cell cycle; regulation of transcription by RNA polymerase II; cell cycle; viral process; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of lipid kinase activity; negative regulation of gene expression; transcription, DNA-templated; negative regulation of cellular senescence; chromatin organization; regulation of mitotic cell cycle; cell differentiation; regulation of cell division; negative regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	5933
	19650
	ENSG00000080839
	ENSMUSG00000027641
	P28749
	Q64701
	NM_002895; NM_183404; NM_001323281; NM_001323282
	NM_001139516; NM_011249
	NP_001310210; NP_001310211; NP_002886; NP_899662
	NP_001132988; NP_035379
	Wikidata
View/Edit Human	View/Edit Mouse

Retinoblastoma-like 1 (p107), also known as RBL1, is a protein that in humans is encoded by the RBL1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000080839 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027641 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).
^ Ewen ME, Xing YG, Lawrence JB, Livingston DM (Sep 1991). "Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein". Cell. 66 (6): 1155–64. doi:10.1016/0092-8674(91)90038-Z. PMID 1833063. S2CID 27478008.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000080839 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027641 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Cite error: The named reference entrez was invoked but never defined (see the help page).

[pmid1833063-6] Ewen ME, Xing YG, Lawrence JB, Livingston DM (Sep 1991). "Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein". Cell. 66 (6): 1155–64. doi:10.1016/0092-8674(91)90038-Z. PMID 1833063. S2CID 27478008.

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