Reversible inhibition of sperm under guidance

Diagram showing the site of injection of the product Vasalgel, a vasectomy alternative

Reversible inhibition of sperm under guidance (RISUG), formerly referred to as the synthetic polymer styrene maleic anhydride (SMA), is the development name of a male contraceptive injection developed at IIT Kharagpur in India by the team of Dr. Sujoy K. Guha.[citation needed]

RISUG has been patented in India, China, Bangladesh, and the United States.[1] Phase III clinical trials were underway in India, and were slowed by insufficient volunteers.[1]

Beginning in 2011, a contraceptive product based on RISUG, Vasalgel, was under development in the US by the Parsemus Foundation, who were unable to bring the product to market over the next decade.[2] In 2023, the patent for Vasalgel was acquired by NEXT Life Sciences, which plans to bring the technology to market under the name Plan A for Men.[3]

  1. ^ a b Jyoti, Archana (2011-01-03). "Poor response from male volunteers hits RISUG clinical trial". The Pioneer. New Delhi. Archived from the original on 2011-06-12. Retrieved 2011-06-08.
  2. ^ Gifford, Bill (2011-04-26). "The Revolutionary New Birth Control Method for Men". Wired. Retrieved 2020-10-19.
  3. ^ Hobbins, Katie (2023-08-22). "'Plan A' Offers a New Option in Male Birth Control". www.mddionline.com.