RhoG

RHOG
Identifiers
Aliases	RHOG, ARHG, RhoG, ras homolog family member G
External IDs	OMIM: 179505; MGI: 1928370; HomoloGene: 68196; GeneCards: RHOG; OMA:RHOG - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 3,826,978 bp[1] End 3,840,959 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E2 Start 101,888,330 bp[2] End 101,905,261 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood monocyte spleen C1 segment bone marrow lymph node olfactory bulb bone marrow cells right lung Top expressed in granulocyte tibiofemoral joint lip bone marrow stroma of bone marrow thymus yolk sac blood spleen pyloric antrum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity protein kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity Cellular component cytosol endoplasmic reticulum membrane membrane focal adhesion plasma membrane extracellular exosome secretory granule membrane intracellular anatomical structure cytoplasm cell cortex cell projection Biological process activation of GTPase activity platelet activation positive regulation of transcription, DNA-templated Rho protein signal transduction positive regulation of cell population proliferation regulation of ruffle assembly cell chemotaxis Rac protein signal transduction regulation of small GTPase mediated signal transduction actin cytoskeleton organization small GTPase mediated signal transduction neutrophil degranulation positive regulation of protein localization to plasma membrane G protein-coupled receptor signaling pathway actin filament organization establishment or maintenance of cell polarity regulation of cell shape regulation of actin cytoskeleton organization phosphatidylinositol phosphate biosynthetic process positive regulation of protein kinase B signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 391 56212 Ensembl ENSG00000177105 ENSMUSG00000073982 UniProt P84095 P84096 RefSeq (mRNA) NM_001665 NM_019566 RefSeq (protein) NP_001656 NP_062512 Location (UCSC) Chr 11: 3.83 – 3.84 Mb Chr 7: 101.89 – 101.91 Mb PubMed search [3] [4]
Wikidata
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RhoG (Ras homology Growth-related) (or ARGH) is a small (~21 kDa) monomeric GTP-binding protein (G protein), and is an important component of many intracellular signalling pathways. It is a member of the Rac subfamily of the Rho family of small G proteins^[5] and is encoded by the gene RHOG.^[6]