Ribose 5-phosphate

Ribose 5-phosphate
Names
IUPAC name
5-O-Phosphono-D-ribose
Other names
Ribose 5-phosphate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.022.101 Edit this at Wikidata
MeSH ribose-5-phosphate
UNII
  • InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1 ☒N
    Key: PPQRONHOSHZGFQ-LMVFSUKVSA-N ☒N
  • InChI=1/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1
    Key: PPQRONHOSHZGFQ-LMVFSUKVBC
  • C([C@H]([C@H]([C@H](C=O)O)O)O)OP(=O)(O)O
Properties
C5H11O8P
Molar mass 230.110
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's state, ribulose 5-phosphate can reversibly isomerize to ribose 5-phosphate. Ribulose 5-phosphate can alternatively undergo a series of isomerizations as well as transaldolations and transketolations that result in the production of other pentose phosphates as well as fructose 6-phosphate and glyceraldehyde 3-phosphate (both intermediates in glycolysis).

The enzyme ribose-phosphate diphosphokinase converts ribose-5-phosphate into phosphoribosyl pyrophosphate.