Richard Gaynor

Richard B. Gaynor is an American physician specializing in hematology-oncology, educator, drug developer, and business executive. He served as an Associate Professor of Medicine at UCLA School of Medicine (Los Angeles, CA) for nearly a decade, and subsequently as an endowed Professor of Medicine and Microbiology at the University of Texas Southwestern Medical School prior to joining the pharmaceutical industry in 2002.[1][2] His research on NF-κB, IκB kinase, and other mechanisms regulating viral and cellular gene expression has been covered in leading subject reviews.[3][4][5][6] He has been a top executive at several pharmaceutical companies,[7] with respect to the development and clinical testing of novel anticancer drugs and cell therapies.[8][9] For over a decade and a half, he worked at Eli Lilly and Company, where he became the Senior Vice President of Oncology Clinical Development and Medical Affairs in 2013.[10] Gaynor was President of R&D at Neon Therapeutics from 2016 to 2020, when he became the President of BioNTech US, both pharmaceutical companies headquartered in Cambridge, MA.[11][12] His honors include being elected a member of the American Society for Clinical Investigation,[13] and the Association of American Physicians.[14]

  1. ^ "Richard B. Gaynor, MD". American Association for Cancer Research (AACR). Retrieved 2022-02-27.
  2. ^ "Richard B. Gaynor, MD – Cancer Progress by Cello Health BioConsulting, Previously Defined Health". Retrieved 2022-02-28.
  3. ^ Tak, Paul P.; Firestein, Gary S. (2001-01-01). "NF-κB: a key role in inflammatory diseases". The Journal of Clinical Investigation. 107 (1): 7–11. doi:10.1172/JCI11830. ISSN 0021-9738. PMC 198552. PMID 11134171.
  4. ^ Li, Qiutang; Verma, Inder M. (2002-10-01). "NF-κB regulation in the immune system". Nature Reviews Immunology. 2 (10): 725–734. doi:10.1038/nri910. ISSN 1474-1733. PMID 12360211. S2CID 6962119.
  5. ^ Hoffmann, Alexander; Levchenko, Andre; Scott, Martin L.; Baltimore, David (2002-11-08). "The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation". Science. 298 (5596): 1241–1245. Bibcode:2002Sci...298.1241H. doi:10.1126/science.1071914. PMID 12424381. S2CID 11834415.
  6. ^ Kingsman, Susan M.; Kingsman, Alan J. (1996-09-15). "The Regulation of Human Immunodeficiency Virus Type-1 Gene Expression". European Journal of Biochemistry. 240 (3): 491–507. doi:10.1111/j.1432-1033.1996.0491h.x. ISSN 0014-2956. PMID 8856047.
  7. ^ "9688.HK Company Profile & Executives - Zai Lab Ltd. - Wall Street Journal". www.wsj.com. Retrieved 2022-02-27.
  8. ^ "New Data On The Combination Of Lilly's ALIMTA (pemetrexed) And Merck's KEYTRUD (pembrolizumab) Show A Near-Doubling Of Objective Response Rate Compared To Standard Of Care Alone In First-Line Metastatic Non-Small Cell Lung Cancer". www.clinicalleader.com. Retrieved 2022-02-27.
  9. ^ "Neon Therapeutics Reports Fourth Quarter and Full Year 2018 Financial Results and Provides Business Update". AP NEWS. 2021-12-17. Retrieved 2022-02-27.
  10. ^ "Document". www.sec.gov. Retrieved 2022-02-27.
  11. ^ "Neon Therapeutics Appoints Dr. Richard Gaynor to President of Research and Development". www.businesswire.com. 2016-11-07. Retrieved 2022-02-27.
  12. ^ Limited, Zai Lab (2021-11-22). "Zai Lab Appoints Richard Gaynor, MD, to its Board of Directors". GlobeNewswire News Room (Press release). Retrieved 2022-02-27. {{cite press release}}: |last= has generic name (help)
  13. ^ "The American Society for Clinical Investigation". Retrieved 2022-04-22.
  14. ^ "Association of American Physicians". aap-online.org. Retrieved 2022-04-22.