Robert S. Coleman

Robert S. Coleman (b 1959) is an American chemistry professor and researcher. Coleman was a faculty member at both Ohio State University and the University of South Carolina. At Ohio State, he was on the faculty in the Department of Chemistry from 1996 to 2012, having moved to Ohio State as an associate professor from the University of South Carolina. At USC, Coleman taught as assistant professor from 1989 to 1995, and then as associate professor (with tenure) from 1995 to 1996. In 1996, he accepted a faculty position at Ohio State University to teach Organic Chemistry, where he was an associate professor from 1996 until 2000. He was promoted to full professor in 2000, teaching Organic Chemistry up until his retirement in 2012. He received his Ph.D. degree working with Professor Dale L. Boger (then at Purdue), completing the first total synthesis of the antitumor agent CC-1065.[1] He was subsequently an NIH postdoctoral fellow at Yale University with Professor Samuel J. Danishefsky, where he completed (with M. Paz Cabal), the first total synthesis of the aglycone of the antitumor agent calicheamicin.[2]

  1. ^ Boger, Dale L.; Coleman, Robert S. (1988). "Total synthesis of (±)-N2-(phenylsulfonyl)-CPI, (±)-CC-1065, (+)-CC-1065, ent-(−)-CC-1065, and the precise, functional agents (±)-CPI-CDPI2, (+)-CPI-CDPI2, and (−)-CPI-CDPI2 \(±)-(3bR*,4aS*)-, (+)-(3bR,4aS)-, and (−)-(3bS,4aR)-deoxy-CC-1065". Journal of the American Chemical Society. 110 (14): 4796. doi:10.1021/ja00222a043.
  2. ^ Cabal, Maria Paz; Coleman, Robert S.; Danishefsky, Samuel J. (1990). "Total synthesis of calicheamicinone: A solution to the problem of the elusive urethane". Journal of the American Chemical Society. 112 (8): 3253. doi:10.1021/ja00164a079.