Robert Wise (1914–2005) was an American film producer and director.
Robert Wise may also refer to:
- Bob Wise (born 1948), American governor of West Virginia
- Chubby Wise (Robert Russell Wise, 1915–1996), American bluegrass fiddler
- Robert C. Wise (1925–2024), American politician in Pennsylvania
- Robert Wise, chairman and managing director of the Wise Music Group, sheet music publishers
- Robert E. Wise, American architect, founder of the Cramer, Bartlett & Wise firm in Los Angeles in the early 1900s
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