Rostom Gurieli (Georgian: როსტომ გურიელი; died 1564), of the House of Gurieli, was Prince of Guria from 1534 until his death in 1564. Alongside his royal suzerain, Bagrat III of Imereti, Rostom fought against the expanding Ottoman Empire to which he lost parts of his principality. Rostom's relations with Bagrat III subsequently deteriorated over his support to the king's defiant vassal, Levan I Dadiani.