Roxan (protein)

ZC3H7B
Identifiers
Aliases	ZC3H7B, RoXaN, zinc finger CCCH-type containing 7B, ROXAN1
External IDs	OMIM: 618206; MGI: 1328310; HomoloGene: 9735; GeneCards: ZC3H7B; OMA:ZC3H7B - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.2 Start 41,301,525 bp[1] End 41,360,147 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E1 Start 81,629,258 bp[2] End 81,680,461 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell buccal mucosa cell nipple renal medulla cardia pylorus superior surface of tongue ventral tegmental area sperm trigeminal ganglion Top expressed in otolith organ hand utricle dentate gyrus of hippocampal formation granule cell Gonadal ridge decidua visual cortex ventricular zone suprachiasmatic nucleus primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein binding RNA binding miRNA binding Cellular component nucleus Biological process viral process posttranscriptional regulation of gene expression production of miRNAs involved in gene silencing by miRNA Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23264 20286 Ensembl ENSG00000100403 ENSMUSG00000022390 UniProt Q9UGR2 F8VPP8 RefSeq (mRNA) NM_017590 NM_001081016 RefSeq (protein) NP_060060 NP_001074485 Location (UCSC) Chr 22: 41.3 – 41.36 Mb Chr 15: 81.63 – 81.68 Mb PubMed search [3] [4]
Wikidata
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RoXaN (Rotavirus 'X'-associated non-structural protein) also known as ZC3H7B (zinc finger CCCH-type containing 7B), is a protein that in humans is encoded by the ZC3H7B gene.^[5] RoXaN is a protein that contains tetratricopeptide repeat and leucine-aspartate repeat as well as zinc finger domains. This protein also interacts with the rotavirus non-structural protein NSP3.^[5]