Rubidium-82 chloride

Rubidium-82 chloride
Names
IUPAC name
Rubidium-82 chloride
Systematic IUPAC name
(82Rb)Rubidium chloride
Identifiers
3D model (JSmol)
ChemSpider
KEGG
UNII
  • InChI=1S/ClH.Rb/h1H;/q;+1/p-1/i;1-3 checkY
    Key: FGDZQCVHDSGLHJ-RYDPDVNUSA-M checkY
  • [Cl-].[82Rb+]
Properties
ClRb
Molar mass 117.371 g mol−1
Pharmacology
V09GX04 (WHO)
Related compounds
Other cations
 Caesium chloride

Lithium chloride
Potassium chloride
Rubidium chloride
Sodium chloride

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Rubidium-82 chloride is a form of rubidium chloride containing a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging.[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.[2] The half-life of rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.[3]

  1. ^ Wackers, Frans J. Th.; Bruni, Wendy; Zaret, Barry L. (2007-11-19). "Rubidium-82 Generator". Nuclear cardiology: the basics: how to set up and maintain a laboratory. Springer. ISBN 978-1-58829-924-6.
  2. ^ Ballinger, James R. (2009). "PET Radiopharmaceuticals in Nuclear Cardiology: Current Status and Limitations". Integrating Cardiology for Nuclear Medicine Physicians. pp. 379–385. doi:10.1007/978-3-540-78674-0_32. ISBN 978-3-540-78673-3.
  3. ^ Gould, K. Lance; Goldstein, Richard A.; Mullani, Nizar A.; Kirkeeide, Richard L.; Wong, Wai-Hoi; Tewson, Timothy J.; Berridge, Marc S.; Bolomey, Leonard A.; Hartz, Ross K.; Smalling, Richard W.; Fuentes, Francisco; Nishikawa, Akira (1986). "Noninvasive assessment of coronary stenoses by myocardial perfusion imaging during pharmacologic coronary vasodilation. VIII. Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced Rubidium-82". Journal of the American College of Cardiology. 7 (4): 775–789. doi:10.1016/S0735-1097(86)80336-9. PMID 3485669.