S. Harris

S. Harris may refer to:

• Sampson Willis Harris (1809-1857), American politician
• Sidney Harris (born 1933), American cartoonist
• Sadie Harris, fictional character from the television show Grey's Anatomy
• S. Harris, co-writer with Juan Tabo of the short story "If You Were an Award, My Love"
• Shyamala Gopalan, married as Shayamala Gopalan Harris