SALL2

SALL2
Identifiers
Aliases	SALL2, COLB, HSAL2, Sal-2, ZNF795, p150(Sal2), spalt-like transcription factor 2, spalt like transcription factor 2
External IDs	OMIM: 602219; MGI: 1354373; HomoloGene: 9269; GeneCards: SALL2; OMA:SALL2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	21,537,216 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	52,566,219 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; superior vestibular nucleus; ; paraflocculus of cerebellum; ; ventral tegmental area; ; ventricular zone; ; inferior olivary nucleus; ; right hemisphere of cerebellum; ; dorsal motor nucleus of vagus nerve; ; pons; ; oocyte;
	Top expressed in
	vestibular sensory epithelium; ; otic vesicle; ; saccule; ; dorsomedial hypothalamic nucleus; ; otic placode; ; median eminence; ; supraoptic nucleus; ; inferior colliculi; ; habenula; ; arcuate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; protein binding; metal ion binding; nucleic acid binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein-containing complex binding;
Cellular component	NuRD complex; nucleus;
Biological process	eye development; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; neural tube development; signal transduction; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6297
	50524
	ENSG00000165821
	ENSMUSG00000049532
	Q9Y467
	Q9QX96
	NM_001291446; NM_001291447; NM_005407; NM_001364564
	NM_001244916; NM_015772
	NP_001278375; NP_001278376; NP_005398; NP_001351493
	NP_001231845; NP_056587
	Wikidata
View/Edit Human	View/Edit Mouse

Sal-like protein 2 is a protein that in humans is encoded by the SALL2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165821 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000049532 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kohlhase J, Schuh R, Dowe G, Kühnlein RP, Jäckle H, Schroeder B, Schulz-Schaeffer W, Kretzschmar HA, Köhler A, Müller U, Raab-Vetter M, Burkhardt E, Engel W, Stick R (December 1996). "Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt". Genomics. 38 (3): 291–8. doi:10.1006/geno.1996.0631. PMID 8975705.
^ "Entrez Gene: SALL2 sal-like 2 (Drosophila)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000165821 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049532 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8975705-5] Kohlhase J, Schuh R, Dowe G, Kühnlein RP, Jäckle H, Schroeder B, Schulz-Schaeffer W, Kretzschmar HA, Köhler A, Müller U, Raab-Vetter M, Burkhardt E, Engel W, Stick R (December 1996). "Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt". Genomics. 38 (3): 291–8. doi:10.1006/geno.1996.0631. PMID 8975705.

[entrez-6] "Entrez Gene: SALL2 sal-like 2 (Drosophila)".

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