SCN3A

SCN3A
Identifiers
Aliases	SCN3A, NAC3, Nav1.3, sodium voltage-gated channel alpha subunit 3, FFEVF4, EIEE62, DEE62
External IDs	OMIM: 182391; MGI: 98249; HomoloGene: 56005; GeneCards: SCN3A; OMA:SCN3A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	165,204,050 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	65,397,971 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; entorhinal cortex; ; Brodmann area 23; ; orbitofrontal cortex; ; Region I of hippocampus proper; ; postcentral gyrus; ; Brodmann area 46; ; cerebellar vermis; ; superior frontal gyrus;
	Top expressed in
	superior cervical ganglion; ; habenula; ; dorsal striatum; ; endothelial cell of lymphatic vessel; ; dorsomedial hypothalamic nucleus; ; ventromedial nucleus; ; piriform cortex; ; paraventricular nucleus of hypothalamus; ; trigeminal ganglion; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sodium channel activity; voltage-gated ion channel activity; ion channel activity; voltage-gated sodium channel activity;
Cellular component	voltage-gated sodium channel complex; cytoplasm; integral component of membrane; membrane; plasma membrane; axon;
Biological process	membrane depolarization during action potential; sodium ion transmembrane transport; sodium ion transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; ion transmembrane transport; neuronal action potential;
	Sources:Amigo / QuickGO
Orthologs
	6328
	20269
	ENSG00000153253
	ENSMUSG00000057182
	Q9NY46
	A2ASI5
	NM_001081676; NM_001081677; NM_006922
NM_018732; NM_001355166; NM_001355167; NM_001355168; NM_001355169;
	NM_001355170; NM_001355171
	NP_001075145; NP_001075146; NP_008853
NP_001342095; NP_001342096; NP_001342097; NP_001342098; NP_001342099;
	NP_001342100; NP_061202
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the SCN3A gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000153253 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000057182 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "UniProt". www.uniprot.org. Retrieved 24 July 2022.
^ "Entrez Gene: SCN3A sodium channel, voltage-gated, type III, alpha subunit".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000153253 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000057182 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[UniProt-5] "UniProt". www.uniprot.org. Retrieved 24 July 2022.

[entrez-6] "Entrez Gene: SCN3A sodium channel, voltage-gated, type III, alpha subunit".

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