SERBP1

SERBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4V6X
Identifiers
Aliases	SERBP1, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1, CGI-55, SERPINE1 mRNA binding protein 1
External IDs	OMIM: 607378; MGI: 1914120; HomoloGene: 134277; GeneCards: SERBP1; OMA:SERBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	67,430,415 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	67,274,720 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; Achilles tendon; ; Skeletal muscle tissue of rectus abdominis; ; mucosa of sigmoid colon; ; skin of thigh; ; trabecular bone; ; parietal pleura; ; vulva; ; triceps brachii muscle; ; ventricular zone;
	Top expressed in
	primitive streak; ; tail of embryo; ; abdominal wall; ; condyle; ; Rostral migratory stream; ; medullary collecting duct; ; hair follicle; ; renal corpuscle; ; endothelial cell of lymphatic vessel; ; otic placode;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; mRNA 3'-UTR binding; RNA binding; cadherin binding; SUMO binding;
Cellular component	perinuclear region of cytoplasm; plasma membrane; extracellular exosome; membrane; cytosol; nucleus; cytoplasm;
Biological process	regulation of apoptotic process; regulation of mRNA stability; PML body organization;
	Sources:Amigo / QuickGO
Orthologs
	26135
	66870
	ENSG00000142864
	ENSMUSG00000036371
	Q8NC51
	Q9CY58
	NM_015640; NM_001018067; NM_001018068; NM_001018069
	NM_001113564; NM_001113565; NM_001113566; NM_025814
	NP_001018077; NP_001018078; NP_001018079; NP_056455
	NP_001107036; NP_001107037; NP_001107038; NP_080090
	Wikidata
View/Edit Human	View/Edit Mouse

Plasminogen activator inhibitor 1 RNA-binding protein (serbp1) is a protein that in humans is encoded by the SERBP1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000142864 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036371 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Heaton JH, Dlakic WM, Dlakic M, Gelehrter TD (May 2001). "Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA". J Biol Chem. 276 (5): 3341–7. doi:10.1074/jbc.M006538200. PMID 11001948.
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
^ "Entrez Gene: SERBP1 SERPINE1 mRNA binding protein 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000142864 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036371 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11001948-5] Heaton JH, Dlakic WM, Dlakic M, Gelehrter TD (May 2001). "Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA". J Biol Chem. 276 (5): 3341–7. doi:10.1074/jbc.M006538200. PMID 11001948.

[pmid10810093-6] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-7] "Entrez Gene: SERBP1 SERPINE1 mRNA binding protein 1".

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