SLC12A8

SLC12A8
Identifiers
Aliases	SLC12A8, CCC9, solute carrier family 12 member 8
External IDs	OMIM: 611316; MGI: 2443672; HomoloGene: 11628; GeneCards: SLC12A8; OMA:SLC12A8 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	125,212,864 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	33,484,505 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; oocyte; ; parotid gland; ; periodontal fiber; ; gallbladder; ; decidua; ; secondary oocyte; ; body of pancreas; ; pancreatic ductal cell;
	Top expressed in
	gastrula; ; submandibular gland; ; parotid gland; ; crypt of lieberkuhn of small intestine; ; duodenum; ; large intestine; ; colon; ; pyloric antrum; ; ileum; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	symporter activity; potassium:chloride symporter activity;
Cellular component	integral component of membrane; membrane;
Biological process	potassium ion transport; ion transport; transmembrane transport; potassium ion transmembrane transport; cell volume homeostasis; chloride ion homeostasis; potassium ion homeostasis; chloride transmembrane transport; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	84561
	171286
	ENSG00000221955
	ENSMUSG00000035506
	A0AV02; H7C5L2
	Q8VI23
	NM_024628; NM_001195483
	NM_001083902; NM_134251; NM_001370999
	NP_001182412; NP_078904
	NP_001077371; NP_599012; NP_001357928
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 12 member 8 (SLC12A8), also known as cation-chloride cotransporter 9 (CCC9), is a protein that in humans is encoded by the SLC12A8 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000221955 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035506 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: solute carrier family 12 (potassium/chloride transporters)".
^ Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I (March 2002). "Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map". Genomics. 79 (3): 305–14. doi:10.1006/geno.2002.6720. PMID 11863360.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000221955 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035506 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: solute carrier family 12 (potassium/chloride transporters)".

[pmid11863360-6] Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I (March 2002). "Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map". Genomics. 79 (3): 305–14. doi:10.1006/geno.2002.6720. PMID 11863360.

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