SMEDI (an acronym of stillbirth, mummification, embryonic death, and infertility) is a reproductive disease of swine caused by Porcine parvovirus (PPV)[1] and Porcine enterovirus. The term SMEDI usually indicates Porcine enterovirus, but it also can indicate Porcine parvovirus, which is a more important cause of the syndrome.[2] SMEDI also causes abortion, neonatal death, and decreased male fertility.
From an economic standpoint SMEDI is an important disease because of the loss of productivity from fetal death in affected herds.[3] Initial infection of a herd causes the greatest effect, but losses slow over time. The disease is spread most commonly by ingestion of food and water contaminated with infected feces and occasionally through sexual contact and contact with aborted tissue.[4] A vaccine is available (ATCvet code: QI09AA02 (WHO)).