 | This article is missing information about outline of taxonomic distribution (eukaryotes and Heimdallarchaeota). (February 2021) |
| SNARE-fusion membrane complex proteins | |
|---|---|
| Identifiers | |
| Symbol | SNARE |
| InterPro | IPR010989 |
| SCOP2 | 1kil / SCOPe / SUPFAM |
| TCDB | 1.F.1 |
| OPM superfamily | 197 |
| OPM protein | 3hd7 |
| Membranome | 198 |
SNARE proteins – "SNAP REceptors" – are a large protein family consisting of at least 24 members in yeasts, more than 60 members in mammalian cells,[2][3] and some numbers in plants.[4] The primary role of SNARE proteins is to mediate the fusion of vesicles with the target membrane; this notably mediates exocytosis, but can also mediate the fusion of vesicles with membrane-bound compartments (such as a lysosome). The best studied SNAREs are those that mediate the release of synaptic vesicles containing neurotransmitters in neurons. These neuronal SNAREs are the targets of the neurotoxins responsible for botulism and tetanus produced by certain bacteria.
- ^ Georgiev DD, Glazebrook JF (2007). "Subneuronal processing of information by solitary waves and stochastic processes". In Lyshevski SE (ed.). Nano and Molecular Electronics Handbook (PDF). Nano and Microengineering Series. CRC Press. pp. 17–1–17–41. doi:10.1201/9781315221670. ISBN 978-0-8493-8528-5.
- ^ Burri L, Lithgow T (January 2004). "A complete set of SNAREs in yeast". Traffic. 5 (1): 45–52. doi:10.1046/j.1600-0854.2003.00151.x. PMID 14675424. S2CID 45480417.
- ^ Gerald K (2002). Cell and Molecular Biology (4th ed.). John Wiley & Sons.
- ^ Raikhel, Natasha V. (2017-04-28). "Firmly Planted, Always Moving". Annual Review of Plant Biology. 68 (1). Annual Reviews: 1–27. doi:10.1146/annurev-arplant-042916-040829. ISSN 1543-5008. PMID 27860488.