SNX2

SNX2
Identifiers
Aliases	SNX2, TRG-9, sorting nexin 2
External IDs	OMIM: 605929; MGI: 1915054; HomoloGene: 2332; GeneCards: SNX2; OMA:SNX2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	122,834,543 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	53,353,937 bp
RNA expression pattern
	Top expressed in
	monocyte; ; Achilles tendon; ; islet of Langerhans; ; ventricular zone; ; gallbladder; ; rectum; ; ganglionic eminence; ; Descending thoracic aorta; ; popliteal artery; ; tibial arteries;
	Top expressed in
	blastocyst; ; yolk sac; ; spleen; ; sciatic nerve; ; placenta; ; morula; ; morula; ; olfactory epithelium; ; uterus; ; stomach;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; insulin receptor binding; leptin receptor binding; epidermal growth factor receptor binding; protein binding; phosphatidylinositol binding; protein heterodimerization activity; transferrin receptor binding; lipid binding; cadherin binding;
Cellular component	cytoplasm; cell projection; early endosome membrane; membrane; retromer, tubulation complex; retromer complex; endosome membrane; lamellipodium; extrinsic component of membrane; cytosol; lysosome; endosome; protein-containing complex;
Biological process	endocytosis; vesicle organization; early endosome to Golgi transport; retrograde transport, endosome to Golgi; protein complex oligomerization; protein transport; intracellular protein transport; lamellipodium morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	6643
	67804
	ENSG00000205302
	ENSMUSG00000034484
	O60749
	Q9CWK8
	NM_003100; NM_001278199
	NM_026386; NM_001357463
	NP_001265128; NP_003091
	NP_080662; NP_001344392
	Wikidata
View/Edit Human	View/Edit Mouse

Sorting nexin-2 is a protein that in humans is encoded by the SNX2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000205302 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034484 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI (Dec 1998). "Identification of a family of sorting nexin molecules and characterization of their association with receptors". Molecular and Cellular Biology. 18 (12): 7278–87. doi:10.1128/mcb.18.12.7278. PMC 109309. PMID 9819414.
^ "Entrez Gene: SNX2 sorting nexin 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000205302 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034484 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9819414-5] Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI (Dec 1998). "Identification of a family of sorting nexin molecules and characterization of their association with receptors". Molecular and Cellular Biology. 18 (12): 7278–87. doi:10.1128/mcb.18.12.7278. PMC 109309. PMID 9819414.

[entrez-6] "Entrez Gene: SNX2 sorting nexin 2".

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