SOAT2

SOAT2
Identifiers
Aliases	SOAT2, ACACT2, ACAT2, ARGP2, sterol O-acyltransferase 2
External IDs	OMIM: 601311; MGI: 1332226; HomoloGene: 68355; GeneCards: SOAT2; OMA:SOAT2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,124,535 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,071,904 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; testicle; ; gonad; ; duodenum; ; spleen; ; right lobe of liver; ; gastric mucosa; ; tibial nerve; ; thoracic aorta; ; ascending aorta;
	Top expressed in
	yolk sac; ; jejunum; ; intestinal villus; ; Ileal epithelium; ; duodenum; ; left lobe of liver; ; perirhinal cortex; ; entorhinal cortex; ; choroid plexus of fourth ventricle; ; primitive streak;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; cholesterol binding; O-acyltransferase activity; fatty-acyl-CoA binding; sterol O-acyltransferase activity; acyltransferase activity; cholesterol O-acyltransferase activity;
Cellular component	membrane; integral component of membrane; brush border; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	very-low-density lipoprotein particle assembly; steroid metabolic process; macrophage derived foam cell differentiation; intestinal cholesterol absorption; cholesterol efflux; lipid metabolism; cholesterol esterification; cholesterol homeostasis; cholesterol metabolic process; low-density lipoprotein particle clearance;
	Sources:Amigo / QuickGO
Orthologs
	8435
	223920
	ENSG00000167780
	ENSMUSG00000023045
	O75908
	O88908
	NM_003578
	NM_146064
	NP_003569
	NP_666176
	Wikidata
View/Edit Human	View/Edit Mouse

Sterol O-acyltransferase 2, also known as SOAT2, is an enzyme that in humans is encoded by the SOAT2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167780 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023045 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SOAT2 sterol O-acyltransferase 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167780 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023045 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SOAT2 sterol O-acyltransferase 2".

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