SQ109

SQ109
Names
Preferred IUPAC name
N1-(Adamantan-2-yl)-N2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]ethane-1,2-diamine
Identifiers
3D model (JSmol)
UNII
  • CC(=CCC/C(=C/CNCCN[C@@H]1C2CC3CC(C2)CC1C3)/C)C
Properties
C22H38N2
Molar mass 330.560 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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SQ109 is a drug undergoing development for treatment of tuberculosis.[1][2]

  1. ^ Jia, L.; Tomaszewski, J. E.; Hanrahan, C.; Coward, L.; Noker, P.; Gorman, G.; Nikonenko, B.; Protopopova, M. (2009). "Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug". British Journal of Pharmacology. 144 (1): 80–87. doi:10.1038/sj.bjp.0705984. PMC 1575972. PMID 15644871.
  2. ^ Meng, Q.; Luo, H.; Liu, Y.; Li, W.; Zhang, W.; Yao, Q. (2009). "Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents". Bioorganic & Medicinal Chemistry Letters. 19 (10): 2808–10. doi:10.1016/j.bmcl.2009.03.091. PMID 19362471.