ST3GAL4

ST3GAL4
Identifiers
Aliases	ST3GAL4, CGS23, NANTA3, SAT3, SIAT4, SIAT4C, ST3GalIV, STZ, ST3 beta-galactoside alpha-2,3-sialyltransferase 4, ST-4, gal-NAc6S, ST3GalA.2
External IDs	OMIM: 104240; MGI: 1316743; HomoloGene: 4572; GeneCards: ST3GAL4; OMA:ST3GAL4 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	126,440,344 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	35,030,564 bp
RNA expression pattern
	Top expressed in
	left adrenal cortex; ; right adrenal cortex; ; left ovary; ; right ovary; ; rectum; ; C1 segment; ; right auricle; ; tibial nerve; ; transverse colon; ; right testis;
	Top expressed in
	Ileal epithelium; ; jejunum; ; gallbladder; ; crypt of lieberkuhn of small intestine; ; molar; ; granulocyte; ; parotid gland; ; submandibular gland; ; duodenum; ; liver;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; glycosyltransferase activity; sialyltransferase activity; beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; monosialoganglioside sialyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; Golgi cisterna membrane; extracellular region; extracellular exosome; membrane; Golgi membrane;
Biological process	cognition; O-glycan processing; keratan sulfate biosynthetic process; oligosaccharide metabolic process; protein N-linked glycosylation via asparagine; protein glycosylation; glycoprotein biosynthetic process; glycolipid biosynthetic process; oligosaccharide biosynthetic process; lipid glycosylation; sialylation; protein sialylation;
	Sources:Amigo / QuickGO
Orthologs
	6484
	20443
	ENSG00000110080
	ENSMUSG00000032038
	Q11206
	Q91Y74
NM_001254757; NM_001254758; NM_001254759; NM_006278; NM_001348396;
	NM_001348398; NM_001348399; NM_001348400; NM_001348397
	NM_009178
NP_001241686; NP_001241687; NP_001241688; NP_006269; NP_001335325;
	NP_001335327; NP_001335328; NP_001335329; NP_001335326
	NP_033204
	Wikidata
View/Edit Human	View/Edit Mouse

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase is an enzyme that in humans is encoded by the ST3GAL4 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110080 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032038 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kitagawa H, Mattei MG, Paulson JC (Feb 1996). "Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase". J Biol Chem. 271 (2): 931–8. doi:10.1074/jbc.271.2.931. PMID 8557707.
^ Kitagawa H, Paulson JC (Feb 1994). "Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups". J Biol Chem. 269 (2): 1394–401. doi:10.1016/S0021-9258(17)42271-X. PMID 8288606.
^ "Entrez Gene: ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000110080 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032038 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8557707-5] Kitagawa H, Mattei MG, Paulson JC (Feb 1996). "Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase". J Biol Chem. 271 (2): 931–8. doi:10.1074/jbc.271.2.931. PMID 8557707.

[pmid8288606-6] Kitagawa H, Paulson JC (Feb 1994). "Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups". J Biol Chem. 269 (2): 1394–401. doi:10.1016/S0021-9258(17)42271-X. PMID 8288606.

[entrez-7] "Entrez Gene: ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4".

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