The Sacchetti family is an Italian noble family originating in Tuscany, now resident in Rome, whose earliest documented member Merlo lived during the late 10th and early 11th centuries.[1] The name of the family is derived from one or more members known as Sacchetto. According to Ugolino di Vieri (1438–1516),"nobile Sacchetti genus est, moenia primus romanus sangius".
In the 19th century, the Sacchetti inherited the title of Prince of Palestrina and permission to use the Barberini name.