Downloadable content for Saints Row: The Third was announced before the game's November 2011 release along with a commitment from publisher THQ to support 40 weeks of content. Among smaller upgrades, three main content packs were released: Genkibowl VII, Gangstas in Space, and The Trouble with Clones. Reviewers found all three packs short—around an hour in length—and considered The Trouble with Clones the best of the bunch.
Genkibowl VII, released in January 2012, brought four new activity types to Steelport around a Professor Genki-themed competition. Sad Panda Skyblazing, the only one of the four activities to not modify an existing activity type, was the reviewers' favorite. Gangstas in Space, released in February, is a three-mission story about a Saints-themed film production starring the player and fighting aliens. The Trouble with Clones, released in March, has the player tracking down and quelling a rampant clone of Saints leader Johnny Gat. Reviewers highly praised its "Saints Flow" superpower sequences, and questioned why they could not have been unlocked in the main game afterwards. All download packs offered unlocks upon their completion.
The Full Package, a version containing all of the game's downloadable content on disc alongside the main game, was released in November. Some of the smaller content items include costume, vehicle, and ability unlocks. THQ planned a standalone expansion of the game called Enter the Dominatrix. It was originally an April Fools' Day prank, that would be spun into Saints Row IV's downloadable content.