Salinispora tropica

Salinispora tropica
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Micromonosporales
Family: Micromonosporaceae
Genus: Salinispora
Species:
S. tropica
Binomial name
Salinispora tropica
Maldonado et al. 2005[1]
Type strain
ATCC BAA-916
CNB-440
DSM 44818
JCM 13857

Salinispora tropica is an obligate marine actinomycete bacterium species.[1] It produces salinosporamide A and salinosporamide B, potential anti-cancer agents,[2][3] as well as the polycyclic macrolides sporolide A and B.[4]

  1. ^ a b Maldonado, L. A. (2005). "Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae". International Journal of Systematic and Evolutionary Microbiology. 55 (5): 1759–1766. doi:10.1099/ijs.0.63625-0. ISSN 1466-5026. PMID 16166663.
  2. ^ Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009). "Discovery and development of the anticancer agent salinosporamide A (NPI-0052)". Bioorganic & Medicinal Chemistry. 17 (6): 2175–2180. doi:10.1016/j.bmc.2008.10.075. PMC 2814440. PMID 19022674.
  3. ^ Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica". The Journal of Organic Chemistry. 70 (16): 6196–203. doi:10.1021/jo050511+. PMID 16050677.
  4. ^ Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica". Organic Letters. 7 (13): 2731–2734. doi:10.1021/ol050901i. PMID 15957933.