Samuel Ashe may refer to:
- Samuel Ashe (North Carolina governor) (1725–1813), American politician, governor of North Carolina
- SS Samuel Ashe, a Liberty ship
- Samuel A'Court Ashe (1840–1938), American politician and Confederate soldier
- Samuel Ashe (MP) (died 1708), English lawyer and politician
This disambiguation page lists articles about people with the same name.
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