Samuel F. Nixon | |
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| Born | Samuel Frederic Nirdlinger 13 October 1848 Fort Wayne, Indiana, USA |
| Died | 13 November 1918 (aged 70) Philadelphia, Pennsylvania, USA |
| Nationality | American |
| Occupation | Theater owner |
| Known for | Theatrical Syndicate |
Samuel F. Nixon, born Samuel Frederic Nirdlinger (13 October 1848 – 13 November 1918) was an American theater owner. He was known as one of the organizers of the Theatrical Syndicate, which monopolized theatrical bookings in the United States for several years.