Santa Catalina de Guale (1602-1702) was a Spanish Franciscan mission and town in Spanish Florida. Part of Spain's effort to convert the Native Americans to Catholicism, Santa Catalina served as the provincial headquarters of the Guale mission province. It also served various non-religious functions, such as providing food and labor for the colonial capital of St. Augustine. The mission was located on St. Catherines Island from 1602 to 1680, then on Sapelo Island from 1680 to 1684, and finally on Amelia Island from 1684 to 1702.