Santa Fe is an unincorporated community in southeastern Monroe County, Missouri, United States.[1] It is located approximately twenty-five miles north of Mexico, near the southern edge of Mark Twain Lake.
Santa Fe was founded in 1836 and named for Santa Fe, New Mexico.[2][3] The post office at Santa Fe has been in operation since 1854.[4]
The Mark Twain State Park Picnic Shelter at Buzzard's Roost was listed on the National Register of Historic Places in 1985.[5] The Clemens family (one of whom was Samuel Clemens, a.k.a. "Mark Twain") owned several tracts of land in the area.