| Santa Fe de Toloca | |
|---|---|
  Location of Santa Fe de Toloca in Florida | |
| Location | Alachua County, Florida, USA |
| Coordinates | 29°55′50.8614″N 82°31′16.4202″W / 29.930794833°N 82.521227833°W |
Santa Fe de Toloca (Teleco, Toloco or Señor Santo Tomás de Santa Fe) was a Spanish mission that existed near the Santa Fe River in the northwestern part of what is now Alachua County, Florida, United States during the 17th century. It became an important place on the camino real (royal road) connecting St. Augustine with Apalachee Province, which was centered on the site of present-day Tallahassee, Florida. The site that the Santa Fe de Toloca mission occupied in the first half of the 17th century was partially excavated in the 1980s.