Seasonal hyperacute panuveitis (SHAPU) is an aggressive eye disease of unknown etiology, first described in 1975.[1] It has been recorded almost exclusively from Nepal, with the exception of five cases reported from Bhutan.[2] The disease affects prevalently children and can cause blindness.[3] In Nepal, it is the most common reported cause of panuveitis, and in children it is the most prevalent cause of both uveitis and panuveitis.[4]