Sehoy III, also called Sehoy Weatherford (c. 1750 – c. 1815) was a Muscogee Creek trader who was part of the Sehoy matrilineage. Like her mother and grandmother, both also called Sehoy, she contracted multiple marriages with white traders. According to Muscogee custom, her sons inherited her tribal identity and later fought on the Creek side of the Creek War and the Red Sticks rebellion. After inheriting property, Sehoy III set herself up as a successful trader in Coosada.