Sekhar may refer to:
- Sekhar Basu, Indian nuclear scientist
- Sekhar Chandra, Indian cricketer
- Sekhar Das (born 1952), Bengali Movie director, scriptwriter
- Ashok Sekhar Ganguly CBE, former chairman of Hindustan Lever, nominated member of the Rajya Sabha
- Sekhar V. Joseph, cinematographer in Kollywood, the Tamil film based industry in South India
- Sekhar Kammula, Indian film director, screenwriter and producer
- Sekhar Menon, Indian actor primarily working in Malayalam cinema and a disc jockey
- Sayan Sekhar Mondal (born 1989), Indian cricketer
- Sukhendu Sekhar Roy, Indian politician belonging to the Trinamool Congress
- Chandra Sekhar Sahu (born 1950), member of the 14th Lok Sabha of India
- Chandra Sekhar Sankurathri, founder of the Sankurathri Foundation
- A Saye Sekhar, Indian journalist, columnist, and a political analyst
- Devineni Raja Sekhar, represents Kankipadu Assembly Constituency in Krishna District, Andhra Pradesh
- G. C. Sekhar, Telugu and Tamil film director
- Guna Sekhar (born 1964), Indian film director and screenwriter
- Krishna Sekhar, Indian film actor
- Master Sekhar, Indian film actor in Tamil film industry
- Samanta Chandra Sekhar (1836–1904), Indian astrologer and scholar
- Raja Ravi Sekhar (born 1954), Indian chess master
- T. A. Sekhar (born 1956), cricketer and medium pace bowler who represented India
- V. Sekhar, Indian film director who has directed Tamil films
- Vinod Sekhar, the President and Group Chief Executive of Petra Group, a Malaysian company
- Sekhar Suri, Indian film director predominately works for Telugu films
- Sekhar Tam Tam MBE, medical doctor, serves on the Grenada Pharmacy Council
- Chandra Sekhar Yeleti (born 1973), Indian film director