Sesquiterpene lactone

Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) and Magnoliaceae (magnolias). A collection of colorless, lipophilic solids, SLs are a rich source of drugs.[1] They can be allergenic and toxic in grazing livestock[2] causing severe neurological problems in horses. Some are also found in corals of the order Alcyonacea.

  1. ^ Ghantous, Akram; Gali-Muhtasib, Hala; Vuorela, Heikki; Saliba, Najat A.; Darwiche, Nadine (2010). "What Made Sesquiterpene Lactones Reach Cancer Clinical Trials?". Drug Discovery Today. 15 (15–16): 668–678. doi:10.1016/0305-1978(86)90101-8. PMID 20541036.
  2. ^ "Sesquiterpene Lactones and their toxicity to livestock". Cornell CALS. Cornell University. Retrieved December 29, 2018.