Set domain containing 1b

SETD1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UVO, 4ES0
Identifiers
Aliases	SETD1B, KMT2G, Set1B, SET domain containing 1B, SET domain containing 1B, histone lysine methyltransferase, IDDSELD
External IDs	OMIM: 611055; MGI: 2652820; HomoloGene: 137311; GeneCards: SETD1B; OMA:SETD1B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	121,832,656 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	123,306,692 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; parietal pleura; ; cardia; ; visceral pleura; ; urethra; ; nipple; ; saphenous vein; ; germinal epithelium; ; seminal vesicula; ; pylorus;
	Top expressed in
	hand; ; otolith organ; ; utricle; ; mesenteric lymph nodes; ; ascending aorta; ; cervix; ; blood; ; granulocyte; ; Gonadal ridge; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleic acid binding; methyltransferase activity; transferase activity; protein binding; histone methyltransferase activity (H3-K4 specific); RNA binding; histone-lysine N-methyltransferase activity;
Cellular component	histone methyltransferase complex; nuclear speck; nucleus; chromosome; nucleoplasm; cytosol; Set1C/COMPASS complex;
Biological process	methylation; regulation of transcription, DNA-templated; transcription, DNA-templated; histone H3-K4 methylation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	23067
	208043
	ENSG00000139718
	ENSMUSG00000038384
	Q9UPS6
	Q8CFT2
	NM_015048; NM_001353345
	NM_001040398; NM_177581
	NP_001340274
	NP_001035488
	Wikidata
View/Edit Human	View/Edit Mouse

SET domain containing 1B is a protein that in humans is encoded by the SETD1B gene. ^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000139718 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038384 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SET domain containing 1B". Retrieved 2018-01-13.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000139718 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038384 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SET domain containing 1B". Retrieved 2018-01-13.

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