The Shakespeare quadrangle is a region of Mercury running from 90 to 180° longitude and 20 to 70° latitude. It is also called Caduceata.
The Borealis quadrangle is north of Shakespeare quadrangle. To the west is Raditladi quadrangle, and to the east is Victoria quadrangle. To the southwest is Tolstoj quadrangle, and to the southeast is Beethoven quadrangle.