Early term for the triplet-repeat pattern of inheritance found in fragile X syndrome
The Sherman paradox was a term used to describe the anomalous pattern of inheritance found in fragile X syndrome.[1] The phenomenon is also referred to as anticipation or dynamic mutation.
- ^ Fu Y, Kuhl D, Pizzuti A, Pieretti M, Sutcliffe J, Richards S, Verkerk A, Holden J, Fenwick R, Warren S (1991). "Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox". Cell. 67 (6): 1047–58. doi:10.1016/0092-8674(91)90283-5. PMID 1760838. S2CID 21970859.