| Shikimate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Shikimate kinase of Erwinia chrysanthemi | |||||||||
| Identifiers | |||||||||
| Symbol | SKI | ||||||||
| Pfam | PF01202 | ||||||||
| Pfam clan | CL0023 | ||||||||
| InterPro | IPR000623 | ||||||||
| PROSITE | PDOC00868 | ||||||||
| SCOP2 | 2shk / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 124 | ||||||||
| OPM protein | 1e6c | ||||||||
| |||||||||
| shikimate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 A cartoon representation of shikimate kinase from Mycobacterium tuberculosis. α-Helices are shown in red, the central β-sheet in yellow, and loops in green | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.1.71 | ||||||||
| CAS no. | 9031-51-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Shikimate kinase (EC 2.7.1.71) is an enzyme that catalyzes the ATP-dependent phosphorylation of shikimate to form shikimate 3-phosphate.[1] This reaction is the fifth step of the shikimate pathway,[2] which is used by plants and bacteria to synthesize the common precursor of aromatic amino acids and secondary metabolites. The systematic name of this enzyme class is ATP:shikimate 3-phosphotransferase. Other names in common use include shikimate kinase (phosphorylating), and shikimate kinase II.
- ^ Morell H, Sprinson DB (February 1968). "Shikimate kinase isoenzymes in Salmonella typhimurium". The Journal of Biological Chemistry. 243 (3): 676–7. doi:10.1016/S0021-9258(18)93656-2. PMID 4866525.
- ^ Herrmann KM, Weaver LM (June 1999). "The Shikimate Pathway". Annual Review of Plant Physiology and Plant Molecular Biology. 50: 473–503. doi:10.1146/annurev.arplant.50.1.473. PMID 15012217.