Shinya Yamanaka

Shinya Yamanaka
Yamanaka in 2010
Born (1962-09-04) September 4, 1962 (age 62)
Higashiōsaka, Osaka, Japan
NationalityJapanese
Alma materKobe University (MD)
Osaka City University (PhD)
Known forInduced pluripotent stem cell
AwardsMeyenburg Prize (2007)
Massry Prize (2008)
Robert Koch Prize (2008)
Shaw Prize (2008)
Gairdner Foundation International Award (2009)
Albert Lasker Basic Medical Research Award (2009)
Balzan Prize (2010)
Kyoto Prize (2010)
BBVA Foundation Frontiers of Knowledge Award (2010)
Wolf Prize (2011)
McEwen Award for Innovation (2011)
Fellow of the National Academy of Sciences[1] (2012)
Millennium Technology Prize (2012)
Nobel Prize in Physiology or Medicine (2012)
Scientific career
FieldsStem cell research[2][3][4]
InstitutionsKyoto University
Nara Institute of Science and Technology
Gladstone Institute of Cardiovascular Disease
University of California, San Francisco
Video of a single beating cardiomyocyte, taken from an open-access article co-authored by Yamanaka.[5] Isolating cells by cell type is an important step in stem cell therapy.
Shinya Yamanaka speaking at a lecture on 2010 January 14
Yamanaka and Ryōji Noyori participating in the ceremony of the 50th All Japan Rugby Football Championship

Shinya Yamanaka (山中 伸弥, Yamanaka Shin'ya, born September 4, 1962) is a Japanese stem cell researcher and a Nobel Prize laureate.[2][3][4] He is a professor and the director emeritus of Center for iPS Cell (induced Pluripotent Stem Cell) Research and Application, Kyoto University;[6] as a senior investigator at the UCSF-affiliated Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisco (UCSF). Yamanaka is also a past president of the International Society for Stem Cell Research (ISSCR).

He received the 2010 BBVA Foundation Frontiers of Knowledge Award in the biomedicine category, the 2011 Wolf Prize in Medicine with Rudolf Jaenisch,[7] and the 2012 Millennium Technology Prize together with Linus Torvalds. In 2012, he and John Gurdon were awarded the Nobel Prize for Physiology or Medicine for the discovery that mature cells can be converted to stem cells.[8] In 2013, he was awarded the $3 million Breakthrough Prize in Life Sciences for his work.

  1. ^ Nair, P. (2012). "Profile of Shinya Yamanaka". Proceedings of the National Academy of Sciences. 109 (24): 9223–9225. Bibcode:2012PNAS..109.9223N. doi:10.1073/pnas.1121498109. PMC 3386100. PMID 22619323.
  2. ^ a b Takahashi, K.; Yamanaka, S. (2006). "Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors". Cell. 126 (4): 663–76. doi:10.1016/j.cell.2006.07.024. hdl:2433/159777. PMID 16904174. S2CID 1565219.
  3. ^ a b Takahashi, K.; Tanabe, K.; Ohnuki, M.; Narita, M.; Ichisaka, T.; Tomoda, K.; Yamanaka, S. (2007). "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors". Cell. 131 (5): 861–872. doi:10.1016/j.cell.2007.11.019. hdl:2433/49782. PMID 18035408. S2CID 8531539.
  4. ^ a b Okita, K.; Ichisaka, T.; Yamanaka, S. (2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 (7151): 313–317. Bibcode:2007Natur.448..313O. doi:10.1038/nature05934. PMID 17554338. S2CID 459050.
  5. ^ Uosaki, H.; Fukushima, H.; Takeuchi, A.; Matsuoka, S.; Nakatsuji, N.; Yamanaka, S.; Yamashita, J. K. (2011). Prosper, Felipe (ed.). "Efficient and Scalable Purification of Cardiomyocytes from Human Embryonic and Induced Pluripotent Stem Cells by VCAM1 Surface Expression". PLOS ONE. 6 (8): e23657. Bibcode:2011PLoSO...623657U. doi:10.1371/journal.pone.0023657. PMC 3158088. PMID 21876760.
  6. ^ "Dept. of Life Science Frontiers Shinya Yamanaka (Director Emeritus & Professor)". Principal Investigators. Center for iPS Cell Research and Application (CiRA), Kyoto University. Archived from the original on September 17, 2023. Retrieved September 17, 2023.
  7. ^ "Shinya Yamanaka - Winner of Wolf Prize in Medicine 2011". Wolf Foundation. 2011. Archived from the original on December 1, 2020. Retrieved January 18, 2023.
  8. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).