 | This article may be too technical for most readers to understand. (September 2023) |
| Shope papilloma virus | |
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| Rabbit with Shope papillomavirus infection | |
Virus classification 
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| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Kappapapillomavirus |
| Species: | Kappapapillomavirus 2
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| Synonyms[1] | |
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The Shope papilloma virus (SPV), also known as cottontail rabbit papilloma virus (CRPV) or Kappapapillomavirus 2, is a papillomavirus which infects certain leporids, causing keratinous carcinomas resembling horns, typically on or near the animal's head. The carcinomas can metastasize or become large enough to interfere with the host's ability to eat, causing starvation. Richard E. Shope investigated the horns and discovered the virus in 1933, an important breakthrough in the study of oncoviruses. The virus was originally discovered in cottontail rabbits in the Midwestern U.S. but can also infect brush rabbits, black-tailed jackrabbits, snowshoe hares, European rabbits,[2] and domestic rabbits.[3]
- ^ "ICTV Taxonomy History for Kappapapillomavirus 2". International Committee on Taxonomy of Viruses. 2014. Retrieved 7 May 2016.
- ^ Van Praag, Ester (2003). "Do Horned Rabbits Really Exist?- Papillomatosis". MediRabbit.com.
- ^ "Rabbit (Shope) Papilloma Virus". dora.missouri.edu. Retrieved 14 September 2023.