Sialic acid binding Ig-like lectin family | |
---|---|
Identifiers | |
Symbol | SIGLEC |
Membranome | 210 |
Siglecs (Sialic acid-binding immunoglobulin-type lectins) are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. There are 14 different mammalian Siglecs, providing an array of different functions based on cell surface receptor-ligand interactions.[1]