 | This article is missing information about overall structure (as context for "S domain" pics and for mechanism description); rough structure and function of binding proteins. (October 2021) |
| signal recognition particle 9kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP9 | ||||||
| NCBI gene | 6726 | ||||||
| HGNC | 11304 | ||||||
| OMIM | 600707 | ||||||
| RefSeq | NM_003133 | ||||||
| UniProt | P49458 | ||||||
| Other data | |||||||
| Locus | Chr. 1 q42.12 | ||||||
| |||||||
| signal recognition particle 14kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP14 | ||||||
| NCBI gene | 6727 | ||||||
| HGNC | 11299 | ||||||
| OMIM | 600708 | ||||||
| RefSeq | NM_003134 | ||||||
| UniProt | P37108 | ||||||
| Other data | |||||||
| Locus | Chr. 15 q22 | ||||||
| |||||||
| signal recognition particle 19kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP19 | ||||||
| NCBI gene | 6728 | ||||||
| HGNC | 11300 | ||||||
| OMIM | 182175 | ||||||
| RefSeq | NM_003135 | ||||||
| UniProt | P09132 | ||||||
| Other data | |||||||
| Locus | Chr. 5 q21-q22 | ||||||
| |||||||
| signal recognition particle 54kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP54 | ||||||
| NCBI gene | 6729 | ||||||
| HGNC | 11301 | ||||||
| OMIM | 604857 | ||||||
| RefSeq | NM_003136 | ||||||
| UniProt | P61011 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q13.2 | ||||||
| |||||||
| signal recognition particle 68kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP68 | ||||||
| NCBI gene | 6730 | ||||||
| HGNC | 11302 | ||||||
| OMIM | 604858 | ||||||
| RefSeq | NM_014230 | ||||||
| UniProt | Q9UHB9 | ||||||
| Other data | |||||||
| Locus | Chr. 17 q25.1 | ||||||
| |||||||
| signal recognition particle 72kDa | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SRP72 | ||||||
| NCBI gene | 6731 | ||||||
| HGNC | 11303 | ||||||
| OMIM | 602122 | ||||||
| RefSeq | NM_006947 | ||||||
| UniProt | O76094 | ||||||
| Other data | |||||||
| Locus | Chr. 4 q11 | ||||||
| |||||||
| Signal recognition particle protein | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ffh | ||||||
| Alt. symbols | p48, Srp54 | ||||||
| UniProt | P0AGD7 | ||||||
| |||||||
The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes.[1]
- ^ Tisdale S, Pellizzoni L (2017-01-01). "Chapter 7 - RNA-Processing Dysfunction in Spinal Muscular Atrophy". In Sumner CJ, Paushkin S, KO CP (eds.). Spinal Muscular Atrophy. Academic Press. pp. 113–131. doi:10.1016/b978-0-12-803685-3.00007-0. ISBN 978-0-12-803685-3.