Medical condition
Sinus node dysfunction Other names Sick sinus syndrome or sinoatrial node disease Telemetry strip of a 44-year-old female with asymptomatic sinus pause found while admitted for mildly symptomatic COVID-19 pneumonia. Complications Tachycardia-bradycardia syndrome Diagnostic method electrocardiogram Treatment Pacemaker implantation
Sinus node dysfunction (SND ), also known as sick sinus syndrome (SSS ), is a group of abnormal heart rhythms (arrhythmias ) usually caused by a malfunction of the sinus node , the heart's primary pacemaker.[ 1] [ 2] Tachycardia-bradycardia syndrome is a variant of sick sinus syndrome in which the arrhythmia alternates between fast and slow heart rates.[ 3]
^ Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, et al. (20 August 2019). "2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society" . Circulation . 140 (8): e382–e482. doi :10.1161/CIR.0000000000000628 . PMID 30586772 .
^ Dobrzynski H, Boyett MR, Anderson RH (10 April 2007). "New Insights Into Pacemaker Activity: Promoting Understanding of Sick Sinus Syndrome" . Circulation . 115 (14): 1921–1932. doi :10.1161/CIRCULATIONAHA.106.616011 . PMID 17420362 .
^ Tse G, Liu T, LiKH, Laxton V, Wong AO, Chan YW, et al. (March 2017). "Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review)" . International Journal of Molecular Medicine . 39 (3): 519–526. doi :10.3892/ijmm.2017.2877 . PMC 5360359 . PMID 28204831 .