The Siska Indian Band (Thompson: sísqeʔ)[1] is located in the Fraser Canyon region of the Canadian province of British Columbia. It was previously a member of the Scw’exmx Tribal Council, which is a tribal council of the Nlaka'pamux people. Other Nlaka'pamux governments belong either to the Fraser Canyon Indian Administration or the Nlaka'pamux Nation Tribal Council, although the large Lytton First Nation, north of Siska, does not belong to any of the three.
The Siska Indian Band reserve community and offices are located adjacent to the Trans-Canada Highway (Hwy 1) between Lytton and Boston Bar.