Sixth Street Historic District may refer to:
- in the United States
(by state)
- Sixth Street Historic District (Grandin, Missouri)
- Sixth Street Historic District (Portsmouth, Ohio), listed on the NRHP in Ohio
- Sixth Street Historic District (Austin, Texas)
- Sixth Street Historic District (Hudson, Wisconsin), listed on the NRHP in Wisconsin
- Douglas-Sixth Street Historic District
- Historic Sixth Street Business District
- South Sixth Street Historic District
- U.S. Route 66-Sixth Street Historic District, Amarillo, TX, listed on the NRHP in Texas
- West Fifth Street-West Sixth Street Historic District
- West Sixth Street and Mayes Place Historic District, Columbia, TN, listed on the NRHP in Tennessee
- West Sixth Street Historic District
This disambiguation page lists articles associated with the title Sixth Street Historic District.
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