Smulders is a Dutch occupational surname. It is a compression of "des mulders", meaning "the miller's son".[1] Notable people with the surname include:
- Ans Smulders (born 1951), Dutch artistic gymnast
- August-Frans Smulders [nl] (1838–1908), shipbuilder
- Carl Smulders [ca; nl; ru] (1863–1934), Dutch composer, pianist and novelist
- Cobie Smulders (born 1982), Canadian actress
- Henri Smulders (1863–1933), Dutch Olympic sailor
- Karina Smulders (born 1980), Dutch actress
- Laura Smulders (born 1993), Dutch bicycle motocross racer
- Margriet Smulders (born 1955), Dutch photographer
- Marlies Smulders (born 1982), Dutch rower
- Truus Smulders-Beliën (1902–1966), Dutch politician and teacher