Sodalis glossinidius

Sodalis glossinidius
Scientific classification
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S. glossinidius

Dale and Maudlin 1999

Sodalis glossinidius is a species of bacteria, the type and only species of its genus. It is a microaerophilic secondary endosymbiont of the tsetse fly. Strain M1T is the type strain.[1] Sodalis glossinidius is the only gammaproteobacterial insect symbiont to be cultured and thus amenable to genetic modification, suggesting that it could be used as part of a control strategy by vectoring antitrypanosome genes. The organism may increase the susceptibility of tsetse flies to trypanosomes.[2]

Despite gene erosion and pseudogene multiplication in a genome of Sodalis glossinidius,[3] these pseudogenes remain actively transcribed.[4]

  1. ^ Dale C, Maudlin I (January 1999). "Sodalis gen. nov. and Sodalis glossinidius sp. nov., a microaerophilic secondary endosymbiont of the tsetse fly Glossina morsitans morsitans". International Journal of Systematic Bacteriology. 49 Pt 1 (1): 267–75. doi:10.1099/00207713-49-1-267. PMID 10028272.
  2. ^ Darby AC, Lagnel J, Matthew CZ, Bourtzis K, Maudlin I, Welburn SC (July 2005). "Extrachromosomal DNA of the symbiont Sodalis glossinidius". Journal of Bacteriology. 187 (14): 5003–7. doi:10.1128/JB.187.14.5003-5007.2005. PMC 1169519. PMID 15995217.
  3. ^ Toh H, Weiss BL, Perkin SA, Yamashita A, Oshima K, Hattori M, Aksoy S (February 2006). "Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host". Genome Research. 16 (2): 149–56. doi:10.1101/gr.4106106. PMC 1361709. PMID 16365377.
  4. ^ Goodhead I, Blow F, Brownridge P, Hughes M, Kenny J, Krishna R, et al. (January 2020). "Large-scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont". Microbial Genomics. 6 (1). doi:10.1099/mgen.0.000285. PMC 7067036. PMID 31922467.